New articles for General Sedation
McPhaden E, Tobias JD, Smith A. Clinical Experience With Remimazolam in Neuroanesthesiology and Neurocritical Care: An Educational Focused Review. J Clin Med Res. 2025 Mar;17(3):125-135. doi: 10.14740/jocmr6193. Epub 2025 Mar 10. PMID: 40115836; PMCID: PMC11922631. Free full text access. Abstract Remimazolam is an ultrashort-acting benzodiazepine, approved for clinical use by the United States Food &…
New articles related to Dentistry
Sun Y, Li Q. Nasopharyngeal airway-assisted sedation enhances oxygenation and reduces perioperative adverse events in pediatric dental surgery: A comparative clinical study. J Investig Med. 2025 May 30:10815589251348914. doi: 10.1177/10815589251348914. Epub ahead of print. PMID: 40444890. Full text access for Children’s and Emory users. Abstract Perioperative airway management during pediatric dental procedures remains challenging, particularly…
New articles relating to MRI
Kim SY, Booth JM, Staffa SJ, Kordun A, Yu J, Cravero JP. A dose-ranging pilot trial of dexmedetomidine-propofol in children undergoing magnetic resonance imaging. J Anesth. 2025 May 11. doi: 10.1007/s00540-025-03511-z. Epub ahead of print. PMID: 40349256. Full text access for Children’s and Emory users. Abstract The optimal sedation/anesthesia technique for magnetic resonance imaging (MRI)…
New articles relating to Ketamine
Udo SI, Rich C, Lyon J. Guideline on the Use of Intravenous Ketamine for Procedural Sedation in the Children’s Emergency Department: A Quality Improvement Project. Cureus. 2024 Dec 4;16(12):e75085. doi: 10.7759/cureus.75085. PMID: 39634206; PMCID: PMC11616467. Free full text access. Abstract In pediatric emergency medicine, sedation is crucial for performing some therapeutic procedures in children. Ketamine…
New articles relating to General Sedation
Bacha T, Kejela S, Hagen SA. Establishing the first ever pediatric procedural sedation clinic in a low-income country: Assessment of the safety and efficacy. BMC Pediatr. 2025 Jan 31;25(1):85. doi: 10.1186/s12887-024-05351-4. PMID: 39891070; PMCID: PMC11783765. Free full text access. Abstract Background: Pediatric sedation clinics are rare in low-income countries. Our aim is to describe the establishment…
New articles relating to Dexmedetomidine
Jin QQ, Cai WC, Zhou YF, Zhang YT, Chen G, Xu MT, Li J, Yuan KM. Comparison of a ready-to-use intranasal dexmedetomidine spray with traditional intranasal dexmedetomidine drops for sedation in preschool children: a prospective, randomized, controlled study. Front Pharmacol. 2025 Jan 23;16:1528612. doi: 10.3389/fphar.2025.1528612. PMID: 39917619; PMCID: PMC11799867. Free full text access. AbstractPurpose: This study…
New articles relating to Dexmedetomidine
Li Y, Jiang Y, Zhang L. The effect of different dosage of intranasal dexmedetomidine on preventing emergence delirium or agitation in children: A network meta-analysis of randomized controlled trials. PLoS One. 2024 Sep 6;19(9):e0304796. doi: 10.1371/journal.pone.0304796. PMID: 39240955; PMCID: PMC11379244. Free full text access. Abstract Background: The clinical evidence for the effects of different doses of…
New articles relating to Ketamine
Wells K, Calleo V. Safety and Depth of Sedation With Ketamine Alone Versus Ketamine With Midazolam in Pediatric Fracture Reduction: A Retrospective Chart Review. Pediatr Emerg Care. 2024 Aug 27. doi: 10.1097/PEC.0000000000003185. Epub ahead of print. PMID: 39190367. Full text access for Children’s and Emory users. Abstract Study objectives: Pediatric patients with extremity fractures often require…
New articles relating to Remimazolam
Pieri M, D’Andria Ursoleo J, Di Prima AL, Bugo S, Barucco G, Licheri M, Losiggio R, Frau G, Monaco F; Collaborators. Remimazolam for anesthesia and sedation in pediatric patients: a scoping review. J Anesth. 2024 Oct;38(5):692-710. doi: 10.1007/s00540-024-03358-w. Epub 2024 Jun 7. PMID: 38844707. Full text access for Children’s and Emory users. Anesthetic management of…
New articles relating to Midazolam
Jampana S, Harrison LC, McCall J, Ferrante RR, Winer JC, Kink RJ, Rogers NG. Evaluation of Intranasal Fentanyl and Midazolam Among Inpatient Pediatric Patients. Hosp Pediatr. 2024 Oct 1;14(10):e439-e442. doi: 10.1542/hpeds.2024-007819. PMID: 39301611. Full text access for Children’s and Emory users. AbstractObjectives: The use of intranasal (IN) analgesics and sedatives has been studied among pediatrics patients…
New articles relating to Oxygenation
Green SM, Bhatt M, Roback MG. Supplemental Oxygen for Pediatric Procedural Sedation: Common Sense Precaution or False Reassurance? Ann Emerg Med. 2024 Jun 21:S0196-0644(24)00293-2. doi: 10.1016/j.annemergmed.2024.05.025. Epub ahead of print. PMID: 38912997. Full text access for Children’s and Emory users. Editorial Should we administer prophylactic supplemental oxygen for procedural sedation? Many clinicians and settings do…
New articles relating to General Sedation
Tom D, Reeves S. Pediatric Procedural Sedation. Pediatr Ann. 2024 Sep;53(9):e324-e329. doi: 10.3928/19382359-20240703-06. Epub 2024 Sep 1. PMID: 39240178. Full text access for Children’s and Emory users. AbstractPediatric procedural sedation (PPS), formerly known as conscious sedation, is often used outside the operating room for various procedures. Twenty years ago, nearly all cases of PPS were…
Safe pediatric procedural sedation and analgesia by anesthesiologists for elective procedures: A clinical practice statement from the European Society for Paediatric Anaesthesiology
Zielinska M, Bartkowska-Sniatkowska A, Becke K, Höhne C, Najafi N, Schaffrath E, Simic D, Vittinghoff M, Veyckemans F, Morton N. Safe pediatric procedural sedation and analgesia by anesthesiologists for elective procedures: A clinical practice statement from the European Society for Paediatric Anaesthesiology. Paediatr Anaesth. 2019 Jun;29(6):583-590. doi: 10.1111/pan.13615. Epub 2019 Mar 13. PMID: 30793427. Full…
Effective and safe pediatric sedation
Jang YE, Kim JT. Effective and safe pediatric sedation. Anesth Pain Med (Seoul). 2024 Jul 23. doi: 10.17085/apm.24046. Epub ahead of print. PMID: 39069650. Full text access for Children’s and Emory users. Abstract Pediatric sedation is a crucial tool for minimizing pain and anxiety during procedures and examinations in children. However, it is not without…
Natural airway as an alternative to intubation for pediatric endoscopic esophageal foreign body removal: A retrospective cohort study of 326 patients
Lonsdale H, Rodriguez K, Shargo R, Ekblad M, Brown JM, Dolan I, Fierstein JL, Miller A, Dey A, Peck J, Rehman MA, Wilsey MJ. Natural airway as an alternative to intubation for pediatric endoscopic esophageal foreign body removal: A retrospective cohort study of 326 patients. Paediatr Anaesth. 2024 Apr 9. doi: 10.1111/pan.14888. Epub ahead of…
A randomized, double-blind, dose-controlled study of the use of dexmedetomidine alone for procedural sedation of children and adolescents undergoing MRI scans
Khan U, Hammer GB, Duncan-Azadi C, Suzuki Y, Chiles D, Chime S, Chappell P. A randomized, double-blind, dose-controlled study of the use of dexmedetomidine alone for procedural sedation of children and adolescents undergoing MRI scans. Paediatr Anaesth. 2024 Feb 16. doi: 10.1111/pan.14857. Epub ahead of print. PMID: 38363011. Full text access for Children’s and Emory…
Comparison of gastric emptying time between breast-fed and formula milk-fed infants less than 6 months old, using gastric ultrasound-An observational study.
Das D, Trikha A, Kaur M, Muthiah T, Pandey RK, Ankalji B, Madhusudhan KS, Srivastava DN, Singh PM. Comparison of gastric emptying time between breast-fed and formula milk-fed infants less than 6 months old, using gastric ultrasound-An observational study. Paediatr Anaesth. 2024 Feb 7. doi: 10.1111/pan.14841. Epub ahead of print. PMID: 38323713. Full text access for…
Efficacy and Safety of Ketamine-Dexmedetomidine Versus Ketamine-Propofol Combination for Periprocedural Sedation: A Systematic Review and Meta-analysis.
Elsaeidy AS, Ahmad AHM, Kohaf NA, Aboutaleb A, Kumar D, Elsaeidy KS, Mohamed OS, Kaye AD, Shehata IM. Efficacy and Safety of Ketamine-Dexmedetomidine Versus Ketamine-Propofol Combination for Periprocedural Sedation: A Systematic Review and Meta-analysis. Curr Pain Headache Rep. 2024 Jan 12. doi: 10.1007/s11916-023-01208-0. Epub ahead of print. PMID: 38214834. Full text access for Children’s and…
Intranasal Dexmedetomidine Use in Pediatric Patients for Anxiolysis in the Emergency Department
Kenneally A, Cummins M, Bailey A, Yackey K, Jones L, Carter C, Dugan A, Baum RA. Intranasal Dexmedetomidine Use in Pediatric Patients for Anxiolysis in the Emergency Department. Pediatr Emerg Care. 2023 Sep 1;39(9):685-691. doi: 10.1097/PEC.0000000000002901. Epub 2023 Jan 5. PMID: 36728557. Full text access for Children’s and Emory users. Abstract Objectives: In recent years, dexmedetomidine…
Multiple General Anesthesia in Children: A Systematic Review of Its Effect on Neurodevelopment
Colletti G, Di Bartolomeo M, Negrello S, Geronemus RG, Cohen B, Chiarini L, Anesi A, Feminò R, Mariotti I, Levitin GM, Rozell-Shannon L, Nocini R. Multiple General Anesthesia in Children: A Systematic Review of Its Effect on Neurodevelopment. J Pers Med. 2023 May 21;13(5):867. doi: 10.3390/jpm13050867. PMID: 37241037; PMCID: PMC10222791. Free full text access. Abstract…
Controversies in anesthesia-induced developmental neurotoxicity
Useinovic N, Jevtovic-Todorovic V. Controversies in anesthesia-induced developmental neurotoxicity. Best Pract Res Clin Anaesthesiol. 2023 Mar;37(1):28-39. doi: 10.1016/j.bpa.2023.03.004. Epub 2023 Mar 27. PMID: 37295851; PMCID: PMC10258891. Full text access for Children’s and Emory users. Abstract Advances in the field of pediatric anesthesiology have enabled the performance of complex and life-saving procedures with minimal patient discomfort.…
Neuroprotective strategies in anesthesia-induced neurotoxicity
Andropoulos DB. Neuroprotective strategies in anesthesia-induced neurotoxicity. Best Pract Res Clin Anaesthesiol. 2023 Mar;37(1):52-62. doi: 10.1016/j.bpa.2022.11.005. Epub 2022 Dec 5. PMID: 37295854. Full text access for Children’s and Emory users. Abstract Over the past 20 years, hundreds of preclinical studies of the developing central nervous system have been published concluding that the common γ-aminobutryic acid…
Clinical Analysis of Intranasal Dexmedetomidine Combined With Midazolam in Pediatric Cranial Magnetic Resonance Examinations
Li SJ, Shen KF, He L, Zhang YP, Ming L, Wu ZF. Clinical Analysis of Intranasal Dexmedetomidine Combined With Midazolam in Pediatric Cranial Magnetic Resonance Examinations. J Perianesth Nurs. 2023 Jun 5:S1089-9472(23)00058-8. doi: 10.1016/j.jopan.2023.02.005. Epub ahead of print. PMID: 37278686. Full text access for Children’s and Emory users. Abstract Purpose: To observe the efficacy and safety…
Regional Anesthesia as an Alternative to Procedural Sedation for Forearm Fracture Reductions in the Pediatric Emergency Department
Sulton CD, Fletcher N, Murphy J, Gillespie S, Burger RK. Regional Anesthesia as an Alternative to Procedural Sedation for Forearm Fracture Reductions in the Pediatric Emergency Department. Pediatr Emerg Care. 2023 Jun 6. doi: 10.1097/PEC.0000000000002993. Epub ahead of print. PMID: 37276083. Full text access for Children’s and Emory users. Abstract Background: Pediatric forearm fractures are common…
Sedation and Analgesia for Reduction of Pediatric Ileocolic Intussusception
Poonai N, Cohen DM, MacDowell D, Mistry RD, Mintegi S, Craig S, Roland D, Miller M, Shavit I; Paediatric Emergency Research Networks (PERN) PAINT Study Group. Sedation and Analgesia for Reduction of Pediatric Ileocolic Intussusception. JAMA Netw Open. 2023 Jun 1;6(6):e2317200. doi: 10.1001/jamanetworkopen.2023.17200. PMID: 37285152; PMCID: PMC10248743. Full text access. Abstract Importance: Ileocolic intussusception is an…
Combination of ketamine and fentanyl (KetaFent) for safe insertion of ultrasound-guided central venous catheters in infants
D’Andrea, V., Prontera, G., Barone, G., & Vento, G. (2023). Combination of ketamine and fentanyl (KetaFent) for safe insertion of ultrasound-guided central venous catheters in infants. Frontiers in pediatrics, 11, 1033793. https://doi.org/10.3389/fped.2023.1033793 Full text access. Abstract Centrally inserted central catheters (CICCs) are placed by ultrasound guided puncture of the internal jugular or brachio-cephalic vein. It is crucial…
Anesthesia and neurodevelopment after 20 years: where are we now and where to next?
Bailey KM, Whyte SD. Anesthesia and neurodevelopment after 20 years: where are we now and where to next? Can J Anaesth. 2022 Dec 19. English. doi: 10.1007/s12630-022-02352-8. Epub ahead of print. PMID: 36536154. Full text access to the Editorial available here for Children’s and Emory users. More on the article discussed in the Editorial: Moser…
Parent and Physician Preference for Anxiolytic Medication Prior to Laceration Repair in Young Children.
Waseem M, Asad H, Shariff MA, Epstein E, Umar Y, Leber M. Parent and Physician Preference for Anxiolytic Medication Prior to Laceration Repair in Young Children. Cureus. 2022 Dec 11;14(12):e32412. doi: 10.7759/cureus.32412. PMID: 36644082; PMCID: PMC9833619. Free full text access. Abstract Pediatric laceration repair is a daunting process for parents and physicians. The repair could…
Prehospital Use of Ketamine Versus Benzodiazepines for Sedation among Pediatric Patients with Behavioral Emergencies
Sandoval S, Goyal A, Frawley J, Gappy R, Chen NW, Crowe RP, Swor R. Prehospital Use of Ketamine Versus Benzodiazepines for Sedation among Pediatric Patients with Behavioral Emergencies. Prehosp Emerg Care. 2023 Jan 11:1-11. doi: 10.1080/10903127.2022.2163326. Epub ahead of print. PMID: 36629484. Full text access for Children’s and Emory users. Abstract Introduction: Ketamine is an emerging…
2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces
Wyckoff MH, Greif R, Morley PT, Ng KC, Olasveengen TM, Singletary EM, Soar J, Cheng A, Drennan IR, Liley HG. 2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First…
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